Introduction ABO hemolytic disease of the newborn is most common cause of neonatal jaundice; previous studies have shown a poor correlation between serologic tests and clinical course in affected infants. The aim of this study was to identify the value of direct and indirect Coombs’ immunohematological tests, to identify the incidence of hemolytic disease in newborns (ABO-HDN). Methods : This  ...

The BrucellaCapt test is an immunocapture agglutination test suggested as a possible substitute for the Coombs test in the diagnosis of human brucellosis. Here it is compared with classical tests using 321 samples from 48 patients with brucellosis (6.9 +/- 1.7 samples per patient), including 20 patients with focal disease and 8 patients with a total of 9 relapse episodes (mean follow-up, 18 mon...

Introduction: A comparative study of blood cross match between gel card technique and conventional tube method wasundertaken on approx 1000 sample conducted in Sanjay Gandhi Memorial Hospital ,Rewa associated with Shyam shahmedical college Rewa .Material & Methods: most commonly conventional tube method are used widly. Now new technique of cross matching isintroduced . In th...

BACKGROUND Many serological tests have been used for the diagnosis of human brucellosis. A new serological method is identified as Brucella Coombs gel test based on the principle of centrifugation gel system similar to the gel system used in blood group determination. In this system, if Brucella antibodies were present in the serum, antigen and antibody would remain as a pink complex on the gel...

The Coombs test (Coombs, Mourant, and Race, 1945a, 1945b, 1946) has become popular as a sensitive and reliable method of detecting incomplete antibodies. The essential reagent is the serum of an animal (usually a rabbit) which has been immunized with human globulin. Potent rabbit sera sometimes show a prozone phenomenon (Wootton, 1950; Van Loghem, Kresner, Coombs, and Fulton Roberts, 1950). The...

S EVERAL RECENT REPORTS have incriminated reticulocytes as the cause of “false positive” Coombs tests obtained in spontaneous or experimentally induced anemia.14 As reticulocytosis is frequently associated with the spontaneous Coombs positive hemolytic anemia which develops in NZB mice, and because the positive Coombs test has been used by Holmes and Burnet5T as the main basis for calling the c...